Drug metabolism and improving energy supplies tissue. Mildronate dihydrate is a synthetic analogue of the gamma-butyrobetaine, a substance found in every cell of the human body.
The mechanism of action determines the diversity of its pharmacological effects: increase efficiency, reduce symptoms of physical and mental stress, activation of tissues and humoral immunity, cardioprotective effect.
Butirobetainhydrooksinaza gamma inhibits, reduces the synthesis of carnitine and fatty acid transport long chain through cell membranes, prevents the accumulation in the cells of the activated forms of unoxidized fatty acids, derivatives and acylcarnitine atsilkofermenta A. in ischemic conditions Mildronate restores the balance between the process oxygen supply and consumption in cells, prevents violation ATP transport; simultaneously active glycolysis, which comes without the use of supplemental oxygen. As a result of reducing the concentration of gamma-butyrobetaine carnitine, which has vasodilatory properties it is synthesized.
Have a cardioprotective effect, it normalizes metabolism of the myocardium. In acute ischemic myocardial lesions Mildronate retards the formation of necrotic areas, shortening the rehabilitation period. In heart failure the drug increases myocardial contractility, increases exercise tolerance, reduces the frequency of angina attacks.
In acute and chronic ischemic cerebrovascular disorders improves blood flow in the ischemic focus, promotes redistribution of blood to the ischemic area.
Effective with vascular and dystrophic pathology fundus.
Has a tonic effect on the central nervous system, it eliminates functional disturbances of somatic and autonomic nervous system in patients with chronic alcoholism during abstinence syndrome. Visit this link to read more about Mildronate from our official site.
